INFORMATION ON ALPHA LIPOIC ACID

Alpha Lipoic Acid (ALA), also known as thioctic acid, is a naturally occuring fatty acid found in every cell in the body. 

With a growing recognition as a mitochondrial antioxidant, it is essential to energy production and acts as an antioxidant, neutralizing cellular damage caused by free radicals. Free radicals can lead to a number of chronic diseases like cancer, heart disease, arthritis, Alzheimer's and Parkinson's.                       

An unusual antioxidant, ALA is both water and fat soluble and can easily cross cell membranes. These unique characteristics enables easier absorption and ALA to work throughout the body, providing protection both inside and outside cells.    

It is highly involved in the Krebs cycle and helps the body convert carbohydrates, proteins and fats into energy, hence their role in blood sugar regulation and benefit in diabetes. Studies have found ALA to positively affect insulin sensitivity, glucose metabolism and diabetic neuropathy.   

ALA passes easily into the brain, protecting brain and nerve tissue and supporting cardiovascular and neurological health. Evidence suggests impressive benefits in the context of  metabolic syndrome, raised cholesterol, multiple sclerosis, stroke, neurological decline, glaucoma, cataracts, premature aging and skin, hair and bone health. 

Although not a true vitamin, ALA functions similar to many B-complex vitamins and appears to recycle antioxidants such as vitamin C, E and glutathione, prolonging their existance in the body and allowing once daily dosing. Glutathione deficiency is associated with low protein intake, liver disease, HIV infection, respiratory distress syndrome, cancer, and idiopathic pulmonary fibrosis.  

How it works:  

Alpha lipoic acid seems to be easily absorbed following oral dosing, and transported by the bloodstream to tissues and cells. Here it is converted into its reduced form DHLA and then transferred into the mitochondria.

ALA and DHLA works both inside and outside cells, and is made up of equal portions of two molecules, known as R and S isomers. Most benefits appear to come from the R configuration, functioning as a cofactor in the Krebs cycle and energy metabolism.

ALA also acts as an antioxidant in both fat-and water-soluble mediums and is capable of regenerating vitamins C and E, and glutathione. 

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