L-glutamine is a conditionally essential amino acid, abundantly present throughout the body. It makes up 61% of the skeletal tissue, the balance circulating in the lung, liver, brain and stomach tissue.
As the principal carrier of nitrogen in the body, L-glutamine is important in protein synthesis, energy metabolism and cell hydration. It helps to strengthen muscles, repair tissue and through secretion of human growth hormone, aids with fat metabolism and blood sugar level maintenance.
It also supports cellular detoxification by eliminating excess ammonia.
Further to its cardiovascular benefits, L-glutamine is essential in the proper functioning of the immune system and digestion, as these cells prefer glutamine as fuel source, rather than glucose. In stressful situations (injuries, infections, burns, trauma or surgical procedures) the release of cortisol can lower glutamine levels, and several studies reported supplementation with glutamine to strengthen the immune system and reduce infections.
L-glutamine supplementation is often used to enhance brain function, as L-glutamine fuels two important neurotransmitters, GABA and glutamic acid.
Providing energy to the brain can support memory, focus and concentration and help to reduce sugar cravings.
How it works:
L-glutamine is synthesized by the body from glutamic acid/glutamate and ammonia. It is produced primarily in the muscles and secondarily in the liver, lungs and brain, providing fuel for many of the body's metabolic processes.
The body uses L-glutamine to create proteins, to regulate acid-base balance (detoxification), for nitrogen donation and to support the production of the super-antioxidant glutathione.
The demand for glutamine increases with physical and mental stress and external supplementation is recommended in such cases.